Both secobarbital capsules and pentobarbital (commonly referred to as the model identify, Nembutal) liquid — (not to be mistaken for epilepsy medication phenobarbital) have already been used both on your own or in combination for health practitioner-assisted suicide or euthanasia. They're also used in injectable types for animal euthanasia.
pentobarbital will lower the extent or influence of venetoclax by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital raises toxicity of ifosfamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. CYP3A4 inducers could enhance the metabolism of ifosfamide to its Energetic alkylating metabolites.
pentobarbital will lessen the extent or influence of estropipate by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the level or effect of colchicine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will reduce the level or effect of eltrombopag by impacting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Keep track of.
pentobarbital will minimize the level or effect of isradipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
pentobarbital will decrease the level or influence of carvedilol by affecting hepatic enzyme CYP2C9/10 metabolism. Use Warning/Monitor.
pentobarbital will reduce the level or result of netupitant/palonosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Netupitant is mainly metabolized by CYP3A4; steer clear of use in individuals who're chronically employing a robust CYP3A4 inducer
pentobarbital will minimize the extent or influence of ramelteon by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.
Insomnia could be the notion or criticism of inadequate or bad-high-quality sleep on account of problems falling asleep; waking up routinely through the evening with problem returning to sleep; waking up as well early each morning; or unrefreshing sleep.
pentobarbital will minimize the level or effect of lumacaftor/ivacaftor by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
pentobarbital will reduce the extent or influence of pimozide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unidentified.
pentobarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Carefully. Coadministration of CYP3A4 inducers may possibly click here minimize sufentanil ranges and efficacy, quite possibly precipitating withdrawal syndrome in people which have developed physical dependence to sufentanil. Discontinuation of concomitantly utilized CYP3A4 inducers could enhance sufentanil plasma concentration.